When international patients visit Seoul for skin care, one of the treatments they ask me about most often is Rejuran. The question is usually the same:
“Why is Rejuran so effective for inner dryness when it doesn’t even contain hyaluronic acid?”
It’s a good question, and the answer comes from clinical experience.
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Why Rejuran Works for Inner Dryness
Rejuran is not simply about adding moisture. Its purpose is to make the dermis healthier so the skin can maintain its own hydration.
Here’s what happens:
- Rejuran stimulates fibroblasts, the cells that produce collagen and elastin.
- As the dermis becomes stronger, the skin develops larger and more numerous moisture reservoirs.
- With more reservoirs, the skin holds water more effectively and stays hydrated for longer.
This explains why patients feel a lasting improvement in inner dryness that creams and topical treatments cannot achieve.
The Key Ingredient: PN (Polynucleotide)
Rejuran’s main component is PN (Polynucleotide)—fragments of DNA.
When PN enters the skin, the body interprets it as a sign of tissue damage. This activates a repair process:
- Fibroblasts are awakened.
- Collagen and elastin production increases.
- The dermis gradually rebuilds itself.
Instead of masking dryness, Rejuran triggers the skin’s own healing response. That is why its effects are structural and long-lasting.
How Polynucleotide works
Why Salmon DNA?
The PN in Rejuran comes from salmon DNA. At first, this may sound unusual, but there are clear reasons.
- Salmon DNA is about 95% similar to human DNA, so immune reactions are minimal.
- It is stable, consistent, and suitable for clinical use.
In my practice, this makes it a safe and reliable material with very few side effects.
What Results Can You Expect?
Immediately after injection, some patients say their skin feels full of moisture. To be honest, that is only the injected solution itself.
The real benefit appears gradually. Over the next several weeks, as collagen and elastin regenerate, patients notice stronger, more elastic skin that holds hydration more effectively.
Rejuran is not a quick cosmetic booster. It is a treatment that trains your skin to stay healthy on its own.
Rejuran: Skin's Gradual Rejuvenation
Why Rejuran Is Worth Trying
Even if you’re only in Korea for a short trip, a single Rejuran session can be worth it. The treatment kickstarts your skin’s natural regeneration, and the benefits continue to show even after you return home.
At DIORE Clinic Gangnam, international visitors can enjoy:
- Private treatment rooms for comfort and privacy,
- Clear explanations in multiple languages,
- Extensive care for international patients.
You can make a free reservation, get a consultation & decide on the procedure after!
[스팟] ✨Creatrip Pick✨ DIORE CLINIC | Free Reservation, Online Consultation Available
Final Thoughts
From a doctor’s point of view, Rejuran is one of the most effective ways to tackle inner dryness. Instead of just adding moisture, it strengthens the dermis and helps your skin hold hydration naturally, giving results that really last.
If you’re looking for Rejuran in Seoul or a reliable clinic in Gangnam for international visitors, DIORE Clinic provides safe, professional care. You can easily book your appointment through Creatrip and enjoy a stress-free experience.
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